MELATONIN 100CAPS – PN

What is Pure Nutrition Melatonin?

Pure Nutrition Melatonin is a pure melatonin supplement designed to help you promote healthy sleep patterns without feeling groggy and drowsy after you wake up. Healthy sleep rhythms are essential for overall well-being, recovery, muscle building, and even fat loss. If you have trouble staying and/or falling asleep, melatonin can help by helping adjust your internal circadian clock. 

Pure Nutrition Melatonin: How it Works

Melatonin is a chemical messenger released by the pineal gland in the brain and ultimately serves to help regulate your circadian clock (which acts like an internal oscillator operating in 24-hour cycles). 
Melatonin secretion is regulated by hormone/neurotransmitter norepinephrine. Exposure to light environments (such as daylight) reduces melatonin synthesis by stopping stimulation of norepinephrine, whereas exposure to dark environments does the opposite. Hence, it’s easier for people to fall asleep when it’s dark outside as opposed to daylight times of the day.

This is why regular circadian rhythms are integral to healthy melatonin production and a healthy sleep-wake cycle. The body also manufactures melatonin by metabolizing the neurotransmitter serotonin, which tends to be decreased in people who are overstressed or depressed. 

Shift workers often struggle to sleep for more than several hours per day as their body is operating on an inverse schedule in terms of their internal circadian clock. If you work late nights as a shift worker, melatonin is highly recommended for helping keep your circadian rhythms in check. 

Health Benefits of Pure Nutrition Melatonin

There are a myriad of benefits of supplementing with Pure Nutrition Melatonin due to its ability to enhance sleep quality and duration. It is well-established that sleep deprivation and erratic sleep patterns can cause a wide range of health problems, including an increased risk of diabetes, obesity, cancer, metabolic syndrome and more.5 As such, melatonin is highly beneficial for people who have trouble falling and staying asleep.
Moreover, clinical research shows that people with irregular sleep patterns and those that work night shifts and/or get jet lag from traveling stand to benefit significantly from melatonin supplementation.4

Furthermore, melatonin is a potent antioxidant with immunomodulating properties, especially in individuals who are undergoing chemotherapy and those who have chronic gastrointestinal issues.6 Antioxidants are molecules that scavenge free radicals and reduce oxidative stress throughout the body.7 
It is primarily recommended to supplement with melatonin for supporting healthy sleep. It may also be a useful supplement for daytime stress management, among a variety of other beneficial properties. 

Overall, clinical evidence and scientific research demonstrates that melatonin has a vast range of benefits, including:

• Promote healthy sleep cycles and circadian rhythms1
• Support healthy growth hormone production2
• May help with insomnia and jet lag3,4 
• Support relaxation and calmness
• Support immune function1
• Promote healthy antioxidant activity6

Pure Nutrition Melatonin Quality Differences

Pure Nutrition Melatonin contains 3 mg of pure melatonin pure serving and is manufactured in a cGMP facility in the USA. It is also free of wheat/gluten, soy, shellfish, milk, egg, tree nuts, artificial colors, and GMOs. It is recommended not to consume more than two servings of Pure Nutrition Melatonin prior to sleep. Do not use melatonin before operating heavy equipment or motor vehicles. 

References

1.  Dubocovich, M. L. (2007). Melatonin receptors: role on sleep and circadian rhythm regulation. Sleep medicine, 8, 34-42.
2.  Smythe, G. A., & Lazarus, L. (1973). Growth hormone regulation by melatonin and serotonin.
3.  Luthringer, R., Muzet, M., Zisapel, N., & Staner, L. (2009). The effect of prolonged-release melatonin on sleep measures and psychomotor performance in elderly patients with insomnia. International clinical psychopharmacology, 24(5), 239-249.
4.  Arendt, J., Skene, D. J., Middleton, B., Lockley, S. W., & Deacon, S. (1997). Efficacy of melatonin treatment in jet lag, shift work, and blindness. Journal of biological rhythms, 12(6), 604-617.
5.  Van Cauter, E., Spiegel, K., Tasali, E., & Leproult, R. (2008). Metabolic consequences of sleep and sleep loss. Sleep medicine, 9, S23-S28.
6.  Blask, D. E., Sauer, L. A., & Dauchy, R. T. (2002). Melatonin as a chronobiotic/anticancer agent: cellular, biochemical, and molecular mechanisms of action and their implications for circadian-based cancer therapy. Current topics in medicinal chemistry, 2(2), 113-132.
7.  Finkel, T., & Holbrook, N. J. (2000). Oxidants, oxidative stress and the biology of ageing. Nature, 408(6809), 239-247.